Your Professional Chlorobutyl Rubber Stopper Manufacturer in China!
Xinxiang Hongfu Bottle Cap Manufacturing Co., Ltd. was established in 2008 with a registered capital of 5 million yuan. In 2013, we were the first in the industry to adopt new production technology, successfully passed inspections from the State Food and Drug Administration twice, and obtained GMP pharmaceutical packaging material certificates. We provide customers in the pharmaceutical and cosmetics industries with high-quality products, including aluminum caps, aluminum-plastic caps, medical glass bottles, and butyl rubber stoppers.
Why Choose Us
Diverse products
Our company has a wide range of products, mainly producing various aluminum plastic caps for antibiotic bottles, oral liquid bottle caps, easy-pierce aluminum caps for oral liquid bottles, various anti-theft aluminum caps, rubber stoppers, medical glass bottles, etc.
Advanced equipment
The fully automatic rivet filling and testing all-in-one machine we own is currently the most advanced production equipment in the industry. From bottle cap riveting, filling, computer detection, counting, the process is completed in one go, significantly improving product quality and efficiency. The production line has a production capacity of 60,000 to 80,000 pieces per hour, and the product qualification rate is 100%.
Broad market
50% of our products are sold domestically, and 50% are exported to more than 20 countries including Southeast Asia, Europe, North America, and South America.
Excellent service
We have 12 hours of online customer service every day to answer your questions about the product. If you have any questions within 7 days of receiving the goods, please contact us and we will compensate or resend. Our customer service will also follow up on product usage.
Infusion rubber stoppers are designed for infusion bottles and provide optimal protection and drug delivery. Infusion rubber stoppers can be used under strong acid and alkali with a good self-sealing property and low fragmentation character. It has a wide application range includes sodium chloride injection, glucose injection and various transfusion drug.
Antibiotic Glass Vial Butyl Rubber Stopper
The existing medical stopper is used, it is very broad. When use, because of the shaking shock in the process of transportation or touch may cause in the process of filling the stopper falls off, at this point that is stored in the bottle of antibiotics will be bacterial contamination of the outside world, lead to a serious medical accident, and the waste of medical resources, therefore, we need to use antibiotics use antibiotic glass vial butyl rubber stopper.
A vial rubber stopper 13 mm used on a vial serves several critical functions, and its design and composition are carefully chosen to ensure the safe and effective storage and transportation of various substances, particularly in the fields of chemistry, pharmacy, and laboratory work.
Butyl rubber stopper is obtained by co-polymerization of isobutylene and isoprene, which come from petroleum. It has a very good impermeability to gas and steam, good resistance to oxidization, ozone, acid and base but poor mechanical properties. Butyl stoppers are therefore used for packing very high hygroscopic powders or lyophilized products or highly oxidizable items. Occasionally, it is used for some applications, such as syringe plungers and droppers.
Rubber vial stoppers allow easy access to drugs contained in glass medication vials, as they can be readily punctured through with a needle or a cannula. In hospitals in general and in intensive care units in particular, the great use of injectable drugs packaged in glass vials with rubber stoppers means that such a practice is very common.
Pharmaceutical Butyl Rubber Stopper
Pharmaceutical Butyl Rubber Stopper is of the highest quality and is manufactured in compliance with the necessary criteria under secure and approved process conditions. This stopper is widely used in pharmaceutical industry for various purposes. And this stopper is very easy to use and simple to handle. A pharmaceutical butyl rubber stopper is employed not just to avoid spills, but also to capture toxic odors and to allow the vessel to be shaken.
In recent years, there has been a growing demand for pharmaceutical rubber stoppers in the healthcare industry. These stoppers are used in the production of various medical products and devices, such as syringes, vials, and IV bags.
In the medical industry, the use of rubber stoppers plug has become indispensable. These small yet essential components serve many critical functions in medical equipment and devices. From protecting medicines from contamination to providing a safe seal for syringes and vials, rubber stoppers are an essential part of the medical supply chain.
The 20mm rubber stopper is a wonderful invention that has revolutionized the way we package and store liquid medicines. It is a small yet mighty tool that ensures the integrity of medications and helps keep them safe from contamination.
Introduction of Chlorobutyl Rubber Stopper
A chlorobutyl rubber stopper is a type of rubber stopper commonly used in the pharmaceutical and healthcare industries. It is made from chlorobutyl rubber, which is a synthetic elastomer derived from butyl rubber through a chlorination process. Butyl rubber, a copolymer of isobutylene and isoprene, has exceptional properties, including gas impermeability, flexibility, and resistance to heat and chemicals. Chlorination introduces chlorine atoms into the butyl rubber's molecular structure, transforming it into chlorobutyl rubber. Chlorobutyl stoppers are often used as closures for vials, bottles, and other containers used to store pharmaceuticals, vaccines, and other medical products. Chlorobutyl rubber stoppers have excellent sealing properties, which help maintain the sterility and integrity of the contents within the container. They have superior heat resistance, making them the preferred choice for applications involving high-heat sterilization techniques.
Seal and Containment
One of the primary functions of a chlorobutyl rubber stopper is to create an airtight and watertight seal, effectively containing the contents within the vial. This hermetic seal is essential for preserving the integrity of the substance inside, be it a chemical compound, medication, or a biological sample. Without a proper seal, the contents could be exposed to the external environment, leading to contamination, degradation, or loss of efficacy.
Chemical Compatibility
Chlorobutyl rubber stoppers are chosen based on their chemical compatibility with the substance they seal. Different compounds and formulations may react with certain materials, so selecting the appropriate rubber stopper ensures that the substance remains stable and uncontaminated.
Tamper-Evidence
In pharmaceuticals and some chemical industries, chlorobutyl rubber stoppers are designed to provide tamper-evidence. Once a vial with a chlorobutyl rubber stopper has been sealed, it is challenging to access the contents without visibly damaging the stopper. This tamper-evident feature is crucial for ensuring the authenticity and safety of pharmaceutical products and other high-value or sensitive substances.
Ease of Removal
While chlorobutyl rubber stoppers provide a secure seal, they are also designed for easy removal when necessary. Vials containing medications, reagents, or samples need to be opened for administration, testing, or analysis. Chlorobutyl rubber stoppers are engineered to be punctured or removed without difficulty, typically using a syringe, needle, or appropriate tools.
Injection and Extraction
In laboratory and medical settings, chlorobutyl rubber stoppers often have self-sealing properties, which allow for repeated injections and extractions without compromising the integrity of the vial's seal. This feature is crucial for processes like liquid chromatography, where samples need to be withdrawn and replaced multiple times.
Pressure and Vacuum Resistance
Chlorobutyl rubber stoppers are designed to withstand varying pressure and vacuum conditions. They are commonly used in laboratory glassware, such as flasks and tubes, where the contents may need to be pressurized or subjected to a vacuum. The elasticity and resilience of rubber allow it to expand or contract as needed to maintain a proper seal.
Durability
The material and design of chlorobutyl rubber stoppers make them highly durable. They are capable of maintaining their sealing properties over time, even when subjected to temperature fluctuations or exposure to chemicals. This durability is essential for long-term storage and transportation of substances.
Sterility
In pharmaceutical and biological applications, chlorobutyl rubber stoppers are sterilized to maintain the sterility of the contents. This is particularly critical in the production of injectable medications and the storage of biological samples. Chlorobutyl rubber stoppers can be sterilized using methods like autoclaving, ensuring that no microorganisms are introduced during sealing.
Reusability
In some cases, chlorobutyl rubber stoppers can be reused after proper sterilization and inspection. This reusability is advantageous for reducing waste and cost, particularly in laboratory settings where frequent vial sealing and unsealing are required.
Size and Compatibility
Chlorobutyl rubber stoppers come in various sizes and shapes to fit different types of vials, bottles, and containers. The compatibility of the stopper with the specific vial ensures a secure and effective seal. This diversity allows for the sealing of a wide range of substances, from small pharmaceutical vials to large chemical containers.
Safety
Chlorobutyl rubber stoppers contribute to the safety of laboratory personnel and the public by preventing leaks and spillage of hazardous substances. Proper sealing with chlorobutyl rubber stoppers minimizes the risk of exposure to harmful chemicals, toxins, or pathogens.
Identification and Labeling
Rubber stoppers are often color-coded or marked with specific symbols to indicate the type of vial content, its properties, or its intended use. This helps prevent mix-ups and ensures that the right substance is used for a particular application.
What is the Difference and Similarities Between Chlorobutyl and Bromobutyl Rubber Stoppers
Similarities
Both chlorobutyl and bromobutyl rubber stoppers are types of butyl rubber stoppers. Both types of rubber undergo a halogenation process, where either chlorine (chlorobutyl) or bromine (bromobutyl) atoms are introduced into the butyl rubber's molecular structure. Moreover, both stoppers share excellent gas impermeability. They generally result in longer shelf lives for pharmaceutical products.
Difference
Definition
Chlorobutyl rubber stoppers are specialized stoppers made of chlorinated butyl rubber, whereas bromobutyl rubber stoppers are specialized stoppers made from brominated butyl rubber.
Stabilizers
Chlorobutyl rubber stoppers do not require stabilizers for production. In contrast, bromobutyl rubber stoppers necessitate the use of stabilizers, such as soybean oil, during their production.
Heat Sensitivity
Bromobutyl rubber stoppers are more heat-sensitive than chlorobutyl rubber stoppers, which have an advantage in their better resistance to heat and are preferred for high-heat sterilization techniques.
Production
Bromobutyl rubber offers faster cure rates and a shorter scorch or cure induction period, resulting in more efficient production, while chlorobutyl rubber requires longer curing times, leading to higher production costs.
Manufacturing Process of Chlorobutyl Rubber Stopper
Formula
It is an operation process of weighing and matching by using a balance according to the raw materials, auxiliaries and dosage ratio specified in the formula.
Mixing
All the necessary ingredients, raw materials and additives, are mixed until a homogeneous mixture is obtained.
Preforming
According to the requirements of different vulcanizing equipment and mold, reducing the mixing glue through the open mixer, or extruder extrusion, calendering machine calendering process into semifinished products.
Vulcanization
At a certain time, temperature, pressure, mixing rubber molecular chain from the linear state into a three-dimensional network of rubber molecular chain. The vulcanization process is a chemical change of rubber macromolecular chain to form a cross-linking process.
Punching and Cutting
That is, trimming, removing the excess waste edge of rubber stopper by mechanical method, so that it can meet the specification requirements of product size.
Cleaning Silicide
The rubber is then cleaned and in some cases siliconized. This typically occurs in "controlled contamination" environments, so-called clean rooms, where there is active air filtration and constant control of key environmental parameters. High-resolution vision systems are also used to perform 100% accurate inspection of parts in the clean room.
Packaging
Usually using clean, electrostatic free polyethylene packaging film packaging, generally divided into inner and outer layers, can be evacuated when necessary. The innermost layer (the first layer) is completed in the clean area of Grade A (100), and the outer layer (the second layer) is completed in the clean area of grade C (10,000). After the inner packaging is completed, it is transferred to the outer packaging area through the transfer window.
What Should be Considered When Choose Chlorobutyl Rubber Stopper
Understand Your Application Requirements
Before diving into the world of chlorobutyl rubber stoppers, it's essential to have a clear understanding of your application's specific requirements. Consider the type of container you are sealing, the nature of the substances involved, and any specific environmental conditions. This initial assessment will guide you in selecting a chlorobutyl rubber stopper that meets the unique demands of your application.
Measurement Basics: Inner and Outer Diameter
The two fundamental measurements for chlorobutyl rubber stoppers are the inner diameter (ID) and outer diameter (OD). The inner diameter refers to the opening size that the stopper will seal, while the outer diameter is the overall size of the stopper. Accurate measurements are crucial for a proper fit, ensuring a tight seal without compromising the integrity of the container.
Consider Tolerance Levels
Tolerance levels play a significant role in the selection process. Tolerance refers to the allowable deviation from the specified dimensions. Understanding the acceptable range of variations is vital to ensure compatibility between the stopper and the container. Always check the product specifications for tolerance information and choose a stopper that aligns with your application's requirements.
Shape and Design
Chlorobutyl rubber stoppers come in different shapes and designs, ranging from standard tapered stoppers to specialty shapes. The shape can impact the ease of insertion and removal, as well as the overall sealing effectiveness. Evaluate the specific requirements of your application to determine the most suitable shape and design for your chlorobutyl rubber stopper.
Consider Regulations and Standards
In certain industries, there are regulations and standards governing the use of chlorobutyl rubber stoppers. Familiarize yourself with any applicable guidelines to ensure compliance. Meeting regulatory requirements is not only essential for safety but also for maintaining the quality and consistency of your processes.
Submit A Quote Request:The process for custom chlorobutyl rubber stoppers development begins with a quote request. You can submit a quote request telling us what you're looking to have produced and we can then provide you with a quote on how much your custom product order would cost.
Send Over Your Design:If the quote looks good to you, the next step will be sending us the custom design you want added to your custom chlorobutyl rubber stopper. Ideally, your design will be in an Adobe Illustrator (.ai) or encapsulated postscript (.eps) format, but we can help you convert the file for free if it isn't. If you don't have a design created, we can help you create a design at no cost!
Review The Proof:Once we have your custom design, we'll then create a proof for you to review so that you can see what your design will look like on your new custom chlorobutyl rubber stoppers. If you approve of the proof, we'll then send you an invoice before beginning production.
Production & Delivery:Once your invoice is paid, we'll begin production. We'll deliver your custom chlorobutyl rubber stoppers straight to you after production. If you don't have the storage for your whole order, we can store a portion of your order for you until you need it.
Our Factory
In 2018, the total investment in our factory exceeded 30 million yuan, and the new factory covers an area of 31 acres. Among them, more than 10 million yuan was invested to build 10,000-level purification workshops, laboratories, and fully automated production lines. Now our factory's annual production capacity has reached 6 billion units, and the 11 fully automatic computer inspection machines we have been currently the most advanced in the industry.
Ultimate FAQ Guide to Chlorobutyl Rubber Stopper
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